For years, Floridians seeking regenerative stem cell therapy had to look beyond state borders, often traveling to Mexico or Colombia. That changed in July 2025, when Florida’s Senate Bill 1768 made it legal for licensed physicians to administer stem cell therapies not yet approved by the FDA for orthopedic conditions, wound care, and pain management. Aspire Rejuvenation has quickly become a leading provider of this therapy in Orlando, offering a legitimate, in-state alternative for patients who want cutting-edge regenerative care without leaving the country.
Aspire’s approach is anchored in medical oversight and ethical sourcing. The clinic uses perinatal tissue allografts derived from placental membrane, umbilical cord tissue, and amniotic membrane donated after healthy, full-term cesarean deliveries with maternal consent. No fetal or embryonic tissue is used, and all tissue comes from FDA-registered laboratories. Every patient begins with a thorough consultation that reviews their medical history, imaging, and treatment goals, ensuring a personalized plan before any injection is administered.
What Is Aspire Rejuvenation?
Aspire Rejuvenation is a multi-location wellness clinic founded in 2019 by Tomo Marjanovic, a former law enforcement officer with more than 12 years of service. The clinic specializes in hormone replacement therapy, peptide therapy, medical weight management, sexual health, and now regenerative medicine—including stem cell therapy. Clinical care is led by Dr. Joseph Clark and a team of licensed nurse practitioners, supported by a comprehensive lab testing and follow-up model.
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The Orlando clinic is the first to offer stem cell therapy under the new Florida law, but Aspire also has locations in Pittsburgh, Ebensburg, and Dallas, with plans to expand to Cleveland and Dubai. The clinic also provides telemedicine services for consultations and follow-ups, making it accessible to patients who cannot visit in person. Aspire’s mission is to help people live healthier, longer lives by addressing root causes of symptoms such as low energy, muscle loss, and weight gain.
What Stands Out About Aspire Rejuvenation
Legal, In-State Stem Cell Therapy
Aspire operates under Florida’s Senate Bill 1768, giving patients a legal, regulated option for stem cell therapy without the expense and risk of international travel. The law requires all stem cells to come from accredited, FDA-registered facilities, and patients must sign a consent form acknowledging the therapy is not FDA-approved. This provides a level of transparency and safety that unregulated clinics abroad cannot guarantee.
Ethical and High-Quality Tissue Sourcing
The clinic uses perinatal tissue allografts from donated placental and umbilical cord tissues. This ethical sourcing avoids the controversy surrounding embryonic stem cells and ensures the tissue is obtained with full maternal consent. All tissue is processed in FDA-registered labs, meeting rigorous quality standards.
Physician-Administered, Low-Risk Procedure
The stem cell injection is given in-office by a licensed physician and takes 30 to 60 minutes. Follow-up visits are scheduled to monitor progress, and the clinic provides ongoing support. This hands-on model emphasizes patient safety and individualized care, which is particularly important for a therapy that is still emerging in the U.S.
Comprehensive Wellness Approach
Aspire does not just offer stem cell injections in isolation. It combines regenerative therapy with hormone optimization, peptide therapy, weight management, and sexual health services. This holistic approach addresses overall wellness, making the clinic a one-stop destination for patients looking to improve their healthspan and vitality.
Who It’s For
Aspire’s stem cell therapy is designed for adults suffering from orthopedic conditions like arthritis, joint pain, or tendon injuries, as well as those dealing with chronic pain or slow-healing wounds. It is also suited for individuals who have considered traveling abroad for stem cell treatment but prefer the convenience and legality of an in-state option. Additionally, patients seeking a comprehensive wellness clinic that offers hormone therapy and weight management alongside regenerative medicine will find Aspire’s integrated approach appealing.
The clinic is not appropriate for everyone, however. Because the therapy is not FDA-approved, patients must be willing to sign an informed consent form acknowledging that. Aspire’s initial consultation helps determine candidacy based on medical history and imaging, ensuring that only those likely to benefit are treated. The clinic does not treat children or pregnant women with stem cell therapy, and any patient with active cancer or certain autoimmune conditions may also be excluded after a medical review.
What Makes It Worth Considering
Aspire Rejuvenation distinguishes itself through its commitment to medical integrity and patient education. Founder Tomo Marjanovic, who received the Public Safety Medal of Valor, brings a sense of discipline and service to the clinic’s culture. The staff prioritizes educating patients about the benefits and limitations of stem cell therapy, helping them make informed decisions rather than overselling results.
The clinic’s multi-location model and telemedicine options add flexibility. Patients can schedule a free initial consultation online, and follow-up visits can be conducted remotely for those who live far from a physical clinic. This makes the service accessible to a broader population. Additionally, Aspire’s long-term focus on healthspan—not just lifespan—aligns with modern wellness trends that emphasize vitality and quality of life.
Verdict
Aspire Rejuvenation offers a credible, physician-led stem cell therapy option in Florida, backed by ethical sourcing and comprehensive patient care. While the therapy is not FDA-approved, the legal framework and rigorous consent process provide a responsible avenue for those seeking regenerative treatment. With strong medical oversight, personalized plans, and a holistic health model, Aspire is a worthy choice for wellness-minded individuals.
Frequently asked questions
Aspire offers physician-administered stem cell injections using perinatal tissue allografts from placental, umbilical cord, and amniotic membranes.
Yes, under Florida Senate Bill 1768, effective July 1, 2025, licensed physicians can perform stem cell therapies not yet FDA-approved for certain conditions.
It is used for orthopedic conditions, wound care, and pain management.
Clinical care is overseen by Dr. Joseph Clark, a licensed physician, along with licensed nurse practitioners.
The injection procedure typically takes 30 to 60 minutes, with follow-up visits scheduled afterward.
No. The clinic uses perinatal tissue from donated placentas and umbilical cords, never from embryos or fetuses.
Clinics are in Orlando, Florida; Pittsburgh and Ebensburg, Pennsylvania; Dallas, Texas; with plans to open in Cleveland and Dubai.
